Lee Health Heart Institute hits major research milestone in global stroke prevention trial

The Lee Health Heart Institute is proud to announce a significant research breakthrough — enrolling its 100th patient in the groundbreaking LeAPPS Clinical Trial, an international study aimed at transforming stroke prevention for cardiac surgery patients.
As one of only 115 sites worldwide and just 10 in Florida, the Lee Health Heart Institute is at the forefront of this crucial study, which explores the effectiveness of left atrial appendage exclusion in preventing stroke and systemic embolism in patients with risk factors for atrial fibrillation and ischemic stroke.
This milestone cements the Heart Institute’s role as a research-driven, life-saving hub in Southwest Florida — bringing world-class clinical innovation to the local community.
“It’s an honor to participate in this essential trial to help reduce stroke risks for cardiac surgery patients,” said Dr. David Cervantes, cardiothoracic surgeon with Lee Health and principal investigator. “We believe these results will significantly enhance patient care in Southwest Florida and help our community access top-quality treatment close to home.”
By participating in cutting-edge clinical trials like LeAPPS, the Lee Health Heart Institute not only helps shape the future of cardiac care — it also ensures that patients right here in Southwest Florida benefit from the latest advances in medical science.
This research could unlock new preventive strategies during cardiothoracic surgeries, lower stroke risk, and drive better long-term outcomes for countless lives.
The Lee Health Heart Institute is the largest heart program in Southwest Florida. It believes in a collaborative approach to cardiac care where cardiac imaging experts work closely with the referring physician to ensure a personalized care plan that meets each patient’s unique needs.
The Lee Health Heart Institute specializes in everything from primary and specialty care, advanced cardiac imaging, cardiothoracic surgery, cardiac rehabilitation and more.
To learn more, please visit leehealth.org/heart.